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But despite widespread use of these drugs by perimenopausal women, research has largely ignored the unique risks and potential opportunities for optimizing health that GLP-1s may pose for this population.

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A randomized controlled clinical trial shows once-weekly semaglutide, when added to cognitive behavioral therapy, significantly reduces heavy drinking days in patients with alcohol use disorder and obesity

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To conclude, the food intake reducing effects of exenatide may temporally evolve from strong anorectic to weak anhedonic modulations, where hedonic experience and anticipation during the early anorectic phase is conserved but uncoupled from food intake behaviour.