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Historically, the development of appetite-suppressing drugs has focused on targeting receptors or transporters of neurotransmitters and neuromodulators released by neurons involved in central feeding regulation

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They then performed 1:1 propensity score matching to create clinically comparable groups in three key analyses

Published studies with metformin use during pregnancy have not reported a clear association with metformin and major birth defect or miscarriage risk (see Data )

Drugs past their expiration date