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If these products truly contained semaglutide or tirzepatide, they would be considered prescription drugs, subject to strict manufacturing standards

Ethics declarations Competing interests The author declares associations with the following companies: Astra-Zeneca, Bristol-Myers Squibb, Merck Sharpe & Dohme, NovoNordisk and Sanofi-Aventis (advisory board membership

while the EULAR Points to Consider provide valuable guidance, the development of standardized criteria will be essential to advance research in this area

Although initial findings suggest that GLP-1Ra leads to a slight reduction in bone mineral density and promotes bone remodeling, favoring resorption similar to calorie restriction effects, further research is needed to explore the effects of GLP-1Ra on bone metabolism and fracture-related outcomes, as well as dual- and triple-receptor agonists of GLP-1, glucose-dependent insulinotropic polypeptide (GIP), and glucagon in PwO

Diabetic patients have reported experiencing worsening blood sugar spikes and higher blood sugar levels than before they started taking the drug

Effect of liraglutide on the dysglycemia, inflammation, and gut microbiota in prediabetic KKay mice
