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Description
GLP-1 was first identified in the 1980s, and since then, its significance in regulating metabolism and its therapeutic potential for diabetes and obesity have been extensively studied
Discrimination between Crigler-Najjar type I and II by expression of mutant bilirubin uridine diphosphate-glucuronosyltransferase

They stand on their own either way

Due to inconsistent reporting of glucoselowering metrics in the included RCTs, we could not assess if the difference in seizure and epilepsy risk was associated with newer GLD's neuroprotective effects from glucose reduction

Understanding your genetic predisposition prevents unnecessary dose delays and helps your provider anticipate which patients might experience stronger or milder side effects

People with longstanding type 2 diabetes often have more advanced beta cell dysfunction and may respond less robustly to GLP-1 therapy
