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The class 5 defects are in the EGF domains and as such affect LDL binding and therefore, this class of mutation exhibits a similar phenotype to the class 3 mutations

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6 BorosL

164 Both proteins harbor a carbohydratebinding globular lectin domain with a prolinerich, hookshaped Pdomain that projects into the lumen and tethers folding catalysts such as ER proteindisulfide isomerases and peptidylprolyl isomerases

Impact of maternal diet on human milk composition and neurological development of infants

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