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ABCG2 protein expression has been further shown to be localized to the apical epithelium of the colon and small intestine, to the liver canalicular membrane and to the surface of cells in breast ducts and lobules (34, 35)

4.1 Iron metabolism-related biomarkers and osteoarthritis 4.1.1 Transferrin receptor 1 (TfR1) TfR1 expression is elevated in OA patients synovial tissue and chondrocytes, making it a potential early diagnostic marker that reflects disease progression

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