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Of particular importance is that free radical damage accumulates with age (Packer, 1994)

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Furthermore, rodent model studies have shown that SCFAs administration can decrease systolic blood pressure mediated by GPR41 expressed in vascular endothelium, while GPR41 knock out mice have isolated systolic hypertension compared with wild-type (WT) mice (Natarajan et al., 2016)

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NT1 is especially suitable for validating our SGB model because all other forms of central hypersomnias are poorly defined and only NT1 is an accepted entity and could thus serve as a referenced ground truth, which is extremely important and crucial for validating the supervised learning model

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