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Moreover, metformin exerts protective effects on skeletal tissue by preventing glucose- and lipotoxicity-induced osteoblast apoptosis and mitigating type 2 diabetes mellitus-associated bone deterioration

In db/db mice, berberine alleviates lipid disorderinduced podocyte injury and delays the progression of diabetic kidney disease (DKD) by reducing lipid accumulation, ROS production, and mitochondrial dysfunction, while restoring fatty acid oxidation [137]

Chinese J

M.DickensB

Serum trimethylamine-N-oxide is elevated in CKD and correlates with coronary atherosclerosis burden

Alternative medical interventions used in the treatment and management of myalgic encephalomyelitis/chronic fatigue syndrome and fibromyalgia