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Free Radic Biol Med 112:111

While urolithin A may be able to promote better mitochondrial health by supporting mitophagy,7 there currently isnt any research to suggest that the compound could benefit primary or genetic mitochondrial diseases (e.g., Leigh syndrome, Kearns-Sayre syndrome, Leber hereditary optic neuropathy, etc.).16 Some experts suggest that it could be worth investigating whether mitophagy activation could act as a novel strategy to treat these diseases, but that research hasnt been conducted yet.17 18 19 When that happens, well update this information

Glutathione, oxidative stress and aging

At the current time, the bioavailability of glutathione is thought to be extremely poor due to the hydrolytic enzymes that break down the glutathione upon ingestion

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