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Ionotropic (fast excitation) and metabotropic glutamate (slow excitation) receptor types are activated by glutamate in the brain (Magalhaes et al., 2012)

The transferrin (Tf) family plays an essential role in transporting ferrum in blood after the formation of ferritin complexes and proliferation, differentiation, and even antioxidation

10.1101/cshperspect.a033688 110 MartinK

& Daglioglu, C

In GBM, this reaction has effects beyond metabolism: -KG acts as a cofactor for KDM6A, a histone demethylase that removes H3K27me3, a repressive epigenetic molecule

10.1016/j.cell.2017.11.048 Cell 41 ItohT.FairallL.AminK.InabaY.SzantoA.BalintB