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Vitamin D is renowned for its ability to modulate immunological function and works in conjunction with Sem to reduce inflammation

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Activation of the canonical Wnt/-catenin pathway is initiated by the binding of Wnt ligands to the Frizzled and Low-density lipoprotein receptor-related protein 5/6 (LRP5/6) receptor complex, which inhibits the phosphorylation and proteasomal degradation of -catenin

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Beydoun MA, Gamaldo AA, Canas JA, Beydoun HA, Shah MT, McNeely JM, Zonderman AB
