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it advocates for integrating CYP2D6 testing into guidelines to enhance safety and precision in child psychiatry, particularly amid barriers like developmental enzyme ontogeny and limited familiarity among clinicians (Singh et al., 2025)

doi: 10.1021/nn4010796 [DOI] [PubMed] [Google Scholar] 261.Crain ML

The presence of the allele CYP2C9*3 has been associated with reduced clearance of phenytoin
Hypofractionated Versus Conventional Fractionated Radiotherapy for Breast Cancer in Patients With Reconstructed Breast: Toxicity Analysis

The LR3 modification increases its half-life, making it more potent and beneficial for muscle regeneration and tissue repair

Yakar et al, 1999
