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Mir-NCM treatment upregulated MT-1/2 expression in striatal astrocytes via 5-HT1A receptors To examine whether mirtazapine upregulated MT-1/2 expression in astrocyte directly or through mesencephalic neurons, primary cultured striatal astrocytes were treated with mirtazapine (2.510 M) or Mir (2.510 M)-NCM for 24 h