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Because of the lack of stable 3D-structures, IDPs can sustain exposure to extremely harsh environmental conditions that would typically denature or unfold ordered proteins and render them dysfunctional (Uversky, 2017b)
Pace Yourself Limit Yourself (standard drink size) Alternate to water Never drink & drive

10.1074/jbc.274.26.18393 18

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Typically, these spots or discolorations are temporary and resolve once the filler dissipates
