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The claim makes biological sense
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Proponents argue this maintains more stable tissue levels, though others find once-daily dosing equally effective with better compliance
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The effects of ANP on lipolysis are more relevant to primates than rodents, as rodents express over 100 times the level of the clearance receptor NP clearance receptor (NPCR), which mitigates the effect of ANP on lipolysis (112, 113)
