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Drugs 27 , 4554 (2022)

MELK promotes HCC carcinogenesis through modulating cuproptosis-related gene DLAT-mediated mitochondrial function

Future research must also prioritize elucidating the precise molecular and biochemical mechanisms by which these therapeutics mediate their effects

These studies suggest that methionine availability controls cell growth and determines cell fates

Hydroxychloroquine A lysomotropic compound that increases pH within acidic vacuoles and alters protein degradation by lysosomal acidic hydrolases, assembly of macromolecules in the endosomes and post-translation modification of proteins in the Golgi apparatus