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more damage to genes

Astrocyteneuron lactate shuttle: mechanisms, signaling functions and controversies Beyond binding to postsynaptic membrane glutamate receptors to generate postsynaptic currents or initiate cell signaling pathways, glutamate released into the synaptic space by the neuronal presynaptic membrane can also be taken up by astrocytes through glutamate transporters

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By modulating pain pathways and reducing inflammation, BPC-157 may help alleviate abdominal pain and cramping associated with IBS, leading to improved comfort and quality of life

Although, the composition and position (i.e., intra- or extracellular) of protein aggregates are different from disease to disease, this common characteristic shows that protein deposition per se , or some related event, is toxic to neurons (Dauer and Przedborski, The pathological changes of PD are characterized by degeneration of DA neurons in the substantia nigra and formation of Lewy body (LB) in neurons (Scherfler et al., 2007)