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Regarding blood pressure, isoprenaline control rats exhibited intracranial (superior sagittal sinus) hypertension, portal and caval hypertension, and aortal hypotension

Prospective evaluation of the efficacy, safety, and optimal biomarker enrichment strategy for nangibotide, a TREM-1 inhibitor, in patients with septic shock (ASTONISH): a double-blind, randomised, controlled, phase 2b trial