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Consequently, adjunctive and hostmodulatory strategies have emerged as promising avenues to enhance treatment outcomes, particularly in challenging clinical scenarios involving local (such as deep periodontal pockets, furcation involvement, or sites showing incomplete response to conventional therapy) or systemic challenges (e.g., smokers and individuals with diabetes mellitus)

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In order to verify the safety/low toxicity of the employed concentrations, we examined the possible apoptotic effects of ALCAR on peripheral blood mononuclear cells (PBMCs) from healthy donors

J Pharmacol Sci 95: 1926

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