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Similarly, this compound inhibits Th17 and Th1 cell differentiation by reducing STAT3 and STAT4 phosphorylation, respectively, and suppresses mTORC1 pathway activity independently of PI3K/AKT and ERK signaling in DSS-induced colitis mice [495]

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The simultaneous exposure to hyperglycaemia and macrophages can increase the migratory potential of PDAC cells through the epithelial-to-mesenchymal transition (EMT) [212]

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