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Moreover, loss of function of GR1 , encoding the cytosol/peroxisome enzymes, causes only moderate GSSG accumulation in leaf tissue, an observation explained by the existence of an auxiliary GSSG-reducing activity ensured by cytosolic NADPH-thioredoxin (TRX) systems (Marty et al., 2009)

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Neurochem Res 14:489493 [DOI] [PubMed] [Google Scholar] 17.Calabrese V, Colombrita C, Sultana R, Scapagnini G, Calvani M, Butterfield DA, Stella AM (2006) Redox modulation of heat shock protein expression by acetylcarnitine in aging brain: relationship to antioxidant status and mitochondrial function

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The methodology for measuring CuEXC through ultrafiltration coupled with atomic absorption spectrometry was first reported in 2009 and applied to healthy individuals to establish reference value ranges (25)