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Cell 187 , 38243828 (2024)
Likewise, targeted disruption of key carnitine shuttle enzymes mediating transport of acetyl-CoA to the cytosol of lymphoma cancer cells for fatty acid synthesis, was shown to cause a cytotoxic depletion of acetyl-CoA and growth inhibition in these cells 69
doi: 10.1016/S0039-6257(97)00090-8
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On the other hand, IGF-1 LR3 may impact osteoblast cell activities, increasing nutrient supply to bone areas and accelerating fracture repairs in organisms during research trials
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