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Given that SODs are characterized as highly efficient enzymes the intracellular (cytosol - SOD1, mitochondria - SOD2) and extracellular (SOD3) balance is shifted towards the formation of H 2 O 2 , which diffuses relatively free or is receptor-mediated transported across biological membranes [9] thereby acting as an intra- and intercellular signaling molecule (Fig

2017;154:R123R131

This can cause dry, itchy, sensitive skin, and worsening of pre-existing conditions such as eczema and dermatitis

Most deep learning models are trained on specific transgenic lines and imaging platforms, and consequently, they often fail to maintain performance when applied to divergent genetic backgrounds or disparate microscope hardware

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Cysteines 208 and 241 in Ero1 are required for maximal catalytic turnover