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Riboflavin, also known as vitamin B2, has to be sourced externally by the mammalian cells from food rich in vitamin B2, such as milk and milk products, eggs, lean meat, salmon, almonds, and spinach

PC12 cells exposed to 6-OHDA showed significant overproductions of both MDA (42.00 3.65 M, Figure 2A) and ROS (228 0.38% of control, Figure 2B) contents compared to control, indicating the induction of oxidative stress and neuronal lipid peroxidation by 6-OHDA

doi: 10.1186/s12964-023-01296-w

Differential roles of RIPK1 and RIPK3 in TNF-induced necroptosis and chemotherapeutic agent-induced cell death

Normal oxidation of NADH or succinate is always a 2-electron reaction, with the transfer of two hydride ions to a flavin