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It recruited 502,713 people (intended to be aged 4069 years, mean age 56.5 years, 45.6% men) from 2006 to 2010 in England, Scotland, and Wales, 94% of self-reported European ancestry

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Funding for the 2019-20 LDHS was provided by the United States Agency for International Development (USAID)

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In the past, research on the carnitine pool focused mainly on FAO, but it has now expanded to many biological fields, including energy metabolism, mitochondrial homeostasis, epigenetic regulation, inflammatory and immune homeostasis, endocrine regulation, cell signaling, neuroprotection, and tumor biology