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Regulatory safety approval for ergothioneine supplementation in humans has only occurred quite recently (2016 in Europe (40) and 2018 in the USA (41) ), and to date only one study has examined ergothioneine supplementation in humans (39)

If you cannot use a vial within 28 days, reconstitute a smaller amount or use a smaller vial size

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doi: 10.3389/fimmu.2021.755862 56 SimpsonDSPangJWeirAKongIYFritschMRashidiMet al