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However, no completed human clinical trials exist, and the compound has not entered formal drug development

doi: 10.1016/j.ijrobp.2009.05.071 27 LiQChenJZhuBJiangMLiuWLuEet al
Tesamorelin: A More Established Peptide Tesamorelin is a synthetic analog of growth hormonereleasing hormone (GHRH) that stimulates the pituitary gland to increase growth hormone secretion, which in turn can reduce visceral (deep abdominal) fat and improve body composition

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The key findings from this clinical program include significant reductions in body weight and fat mass in treatment groups compared to placebo, preferential loss of abdominal and visceral adipose tissue, no changes in serum IGF-1 levels at any dose tested, no negative effects on glucose metabolism or insulin sensitivity, no significant adverse events related to metabolic or endocrine disruption, and safety profile indistinguishable from placebo for most parameters

"On the mechanism of catalysis by vitamin B12"
