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However, only 74 articles were included after screening and quality assessment based on abstract and full-text documents (Fig

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However, soluble -synuclein undergoes aggregation and misfolding under various pathological conditions, including compromised membrane-binding capacity, exposure to dopamine oxidation products or metal ions, or impaired autophagy/proteasome degradation system

Imbalance in the generation of ROS is a common feature in several diseases, including neurodegeneration disorders, metabolic disorders, cardiovascular disease, and cancer [80]

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