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doi: 10.3389/fimmu.2022.784046 Received 27 September 2021 Accepted 21 February 2022 Published 16 March 2022 Volume 13 - 2022 Edited by Laurence Macia, The University of Sydney, Australia Reviewed by Tina Srensen Dalgaard, Aarhus University, Denmark

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Both trials found that a moderate dose of bupropion SR (typically 150 mg daily) led to greater improvements in fatigue scores over ~ 6 to 8 weeks compared to placebo [68, 69]

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However, recovery also depends on other factors like rest, nutrition and hydration