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Glutamate is strongly implicated in chemotherapy neurotoxicity (Carozzi et al, 2009) and compounds that inhibit glutamate production have been shown to reduce neuronal damage (particularly in the dorsal root ganglia ) in rat models (Carozzi et al)

A wide array of agents has been shown to decrease radiation-induced DNA damage in human lymphocytes

Proc Natl Acad Sci USA 97:1438214387 Philip P, Sagaspe P, Taillard J et al (2019) Acute intake of a grape and blueberry polyphenol-rich extract ameliorates cognitive performance in healthy young adults during a sustained cognitive effort

The released Cur could notably decrease intracellular GSH content and thus improve the chemosensitivity of CDDP, resulting in severe cellular apoptosis

Greibe, E

Ebbing M, Bnaa KH, Nygrd O, Arnesen E, Ueland PM, Nordrehaug JE, Rasmussen K, Njlstad I, Refsum H, Nilsen DW, Tverdal A, Meyer K, Vollset SE