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Res Sq2024 Jun 06

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The metabolic effects of insulin cannot be fully compensated by insulin-like growth factor-1 (IGF-1) or by alternative mechanisms [185,186]

Since the EGFR C797S mutant protein confers resistance to the inhibitor osimertinib, PROTAC could be a promising alternative treatment for lung cancer patients harboring this mutation 137

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[4] The 1500 mcg dose is not just a number
