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TABLE 6 Pharmacokinetic parameters of BPC157 in dogs following repeated intramuscular administration at a dose of 30 g/kg for seven consecutive days (mean SD, n = 6)
Sanger sequencing revealed a germline insertion in NF1 exon 2 (c.165_166insCT), causing a frameshift and premature truncation that likely disrupted NF1 function in patient iPSCs (Fig
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These mechanisms can interact and self-perpetuate, leading over time to impaired lung function
