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This again suggests the critical role of peroxynitriterather than LPOas the primary cause of oxidative damage to mitochondrial DNA 18 and protein nitration, which are central mechanisms of toxicity (Fig

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Fatty fish are, of course, particularly susceptible to lipid degradation which can create severe quality problems even on storage at subzero temperatures

Additionally, water-based methods are particularly effective for extracting polar compounds, such as phenolic acids and flavonoids, which are often associated with antioxidant activity (Santos et al., 2022)