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To further examine the effects of serine synthesis on Np63-mediated carboplatin resistance in vivo, we generated xenograft models by subcutaneously injecting transfected LUSC cells into nude mice, followed by treatment with carboplatin and/or NCT-503, an inhibitor of PHGDH (Fig

Following PRISMA guidelines, seven eligible RCTs were identified from databases including PubMed, Scopus, and ScienceDirect

Engrailed genes are cell-autonomously required to prevent apoptosis in mesencephalic dopaminergic neurons

Decreased expression of cytochrome P450 2E1 is associated with poor prognosis of hepatocellular carcinoma

Under these conditions and based on the preventive action of NAC on HIC, alternative mechanisms lead to the abrogation of HIC by NAC

Furthermore, a sample of the crosslinking reaction was analysed on an SDS-PAGE gel
