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Although ARA 290 has a short serum half-life of a few minutes (11), the peak plasma concentrations attained after the administration of 2 mg intravenously in normal human volunteers in pharmacokinetic studies reached ~50 ng/mL, exceeding the minimum effective peak concentration of ~1 ng/mL (26)

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170 KakanisMWPeakeJBrenuEWSimmondsMGrayBMarshall-GradisnikSM

[DOI] [PMC free article] [PubMed] [Google Scholar] 174.Weersma RK, Zhernakova A, Fu J

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Some people may experience mild side effects such as nausea, headache, or diarrhea