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Affinity Water provides on average 900 million litres of water each day to a population of more than 3.6 million people in North West London and the Home Counties serving Bedfordshire, Berkshire, Buckinghamshire, Essex, Hertfordshire, Surrey, the London Boroughs of Harrow and Hillingdon and parts of the London Boroughs of Barnet, Brent, Ealing and Enfield

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An earlier LEGEND Hypertension study, published in The Lancet, found that thiazide diuretics were more effective and caused fewer side effects than ACE inhibitors when used as first-line antihypertensive drugs

Overexpressed IGFBP-1 in transgenic mice shows that its increase produces hyperinsulinaemia accompanied by glucose intolerance, and that this process is dependent upon IGFBP-1 phosphorylation statewhich is increased in diabetes [259]

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