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(2): Acid effects (AE) were evaluated as a percentage ratio of the analyte peak area in a standard solution prepared in the acidic extraction solvent to the peak area of the same standard prepared in a solvent without acid

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et al., 2022) and can reduce intestinal 5-Hydroxytryptamine (5-HT) signaling by lowering tryptophan hydroxylase-1 (TPH1) expression levels, thereby alleviating visceral hypersensitivity (Zhao et al., 2020)

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[DOI] [PMC free article] [PubMed] [Google Scholar] 102.Jun HJ, et al