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mimetics include certain N-acyl groups as specified in Table 1 (Family 1), in the practice of various embodiments of the invention other N-acyl groups or substituted or unsubstituted phenyl groups may be used at i

Combined use demonstrates improved outcomes in animal research, including: Faster formation of granulation tissue and wound closure Reduced edema and inflammation Enhanced tendon-to-bone integration and ligament tensile strength Systemic protection of organs such as liver and kidney in ischemia-reperfusion models Systematic reviews of over 35 preclinical studies consistently report positive histological and functional results, with no observed toxicity

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Injection sites must also be rotated to prevent irritation and lipodystrophy, which causes fatty lumps on the body