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doi: 10.1093/humrep/del428 67 AitkenRJDe IuliisGN

Lack of physical activity (sedentary lifestyle), poor blood circulation , dehydration (drinking insufficient amount of water), stress, irritability, anxiety , and depression are also associated with the development of RLS

J Cell Signal

Although this competitive phenomenon has not yet been observed in the brain, it may be a significant reason for the poor efficacy and side effects of many therapeutic approaches, warranting further investigation

Key knowledge gaps are identified, particularly in large-scale deployment, multi-season field trials, and standardized assessment protocols across diverse agroecosystems

Kozarski M, Klaus A, Niksic M, Jakovljevic D, Helsper JPFG, Van Griensven LJLD