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doi: 10.1007/s12264-007-0031-0

However, impaired mitochondrial -oxidation of fatty acids was observed which could have a negative effect on insulin sensitivity (99)

If there is a deficiency of folate, it will lead to the obstruction of DNA synthesis, and increase the volume of cells but prevent them from maturing, thereby causing megaloblastic anemia

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Finally, a second regulatory region, the regulatory insertion (residues 615-643), interacts with the R-domain through an electrostatic or H-bond interaction from K617 to S903, another residue that is known to be phosphorylated (Supplementary Fig

In contrast, 1-Cys Prx family members (i.e., human Prx6) lack a resolving cysteine and are likely reduced by GSH (Figure 1)