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From the condensation of one molecule of 4-coumaroyl CoA (from Phe) and three of malonyl CoA (from fatty acid metabolism), through the combined consecutive actions of three different enzymeschalcone synthase, chalcone isomerase (CHI), and flavanone 3-hydroxylase the dihydroflavonol dihydrokaempferol is produced
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The findings from our study suggest that antioxidant use in males diagnosed with IMI and UMI led to notable improvements in semen parameters and sperm function, as documented in methodologically rigorous studies

For two group comparisons, the significance of differences was assessed using the t -test for normally distributed data or the MannWhitney test for deviations from normality
