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10.1126/science.1117311 50 HalliwellB

Sequential DICE combined with l-asparaginase chemotherapy followed by involved field radiation in newly diagnosed, stage IE to IIE, nasal and extranodal NK/T-cell lymphoma

71 HiltonD.StephensM.KirkL.EdwardsP.PotterR.ZajicekJ.et al (2014)

Skin health starts inside

Depletion of MT3 decreased mitochondrial ROS levels in osteoclast precursors ROS activates the downstream mediator peroxisome proliferator-activated receptor coactivator 1 (PGC-1) via phosphorylating the cAMP response element-binding protein (CREB) during osteoclastogenesis, stimulating mitochondrial biogenesis, and the generating of mitochondrial ROS, which in a positively feedback-induced manner increases CREB and PGC-1 activity and facilitates NFATc1 activation [11, 12, 44, 45]