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Analysis of the IDH1 codon 132 mutation in brain tumors
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Paul C and Brady DM
This is associated with swelling of the axon and formation of axonal spheroids
Front Pharmacol 9:686 Mathur M, Ramawat KG (2007) Guggulsterone production in cell suspension cultures of the guggul tree, Commiphora wightii , grown in shake flasks and bioreactors
The study reported no significant toxicity, apart from gastrointestinal symptoms (diarrhea, nausea, and flatulence) which were managed symptomatically with minimal impact on quality of life 97
