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Hypoxia can also induce HIF-1-mediated expression of lncRNA-CBSLR, which recruits YTHDF2 to read m 6 A-modified CBS (cystathionine -synthase) mRNAs, leading to decreased mRNA stability and reduced CBS expression

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mPFC: 22 ASD (2F/20M) and 21 TDC (6F/15M)

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A) Mitochondrial generation of superoxide is a characteristic feature of APAP-induced hepatocyte cell death, which reacts with nitric oxide to form the highly reactive oxidant and nitrating species peroxynitrite, causing extensive protein nitration in mitochondria