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Ghaffari, 2022)

Heightened PLA2 expression in these lesions triggers irregular lipid metabolic pathways, fostering excessive cellular proliferation, inflammatory cytokine release, flawed keratinization, and uncontrolled cell migration (95)

The first two clinical trials are currently in the recruitment phase, focusing on evaluating the safety and efficacy of their respective stem cell treatments on distinct sample groups

PPAR-related coactivator 1 (PRC

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However, despite its protective role, the constant activation of the Nfr2 pathway in response to e-cigarette use, particularly the flavouring agents found in e-cigarettes, can exhaust this protective pathway, leading to eventual cellular death in the epithelium (Ma et al