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It is important to note that the majority of this mechanistic research has been conducted in cell culture and animal models, with a significant proportion originating from a single research group

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Also, NSAIDs, while lacking addictive potential, can cause a range of complications, such as upper gastrointestinal bleeding [23,66] and renal dysfunction [67,68]

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A small number of individuals requested that they be provided an alternative treatment and nearly half of respondents stated that they were unsure how long the change to their treatment would last