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2.2 Epithelial barrier disruption and aberrant repair mechanisms Under physiological conditions, epithelial cells in both the gut and respiratory tract maintain barrier integrity by producing immunoglobulin A (IgA), defensins, and lysozyme, thereby preventing microbial invasion and regulating immune homeostasis (Losol et al., 2023)

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doi: 10.3390/livers2040023

This is especially important for pediatric patients

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