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About this article Cite this article Fan, Z., Yang, C., Qu, X

doi: 10.1002/14651858.CD003868.pub3

Second, glutathione synthetase combines gamma-glutamylcysteine with glycine to generate glutathione

The original online version of this Article was revised: The original version of the Article contained an error in the Author Contributions section

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Brabetz and his co-authors generated PDX-derived 3D organoids retaining genetic and transcriptional heterogeneity of primary tumors that were strategic to demonstrate that group 3 organoids with MYC amplification exhibit invasive growth patterns depending on the 3D extracellular matrix (ECM) (such as collagen) and that venetoclax (a BCL-2 inhibitor) synergizes with chemotherapy, overcoming apoptosis resistance (115, 116)