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Many drugs, including clarinex, donezepil, raloxifene, and methylphenidate, have been found to have piperidine as their principal chromophore [128]

During the novel object recognition (NOR) tests, gradually deteriorating short-term (1-h) and long-term (24-h) cognitive impairments occurred with the increasing time of ethanol exposure, while earlier and severer recognition memory loss were found in APP/PS1 mice, compared to WT mice (Fig

Lister A, Nedjadi T, Kitteringham NR et al (2011) Nrf2 is overexpressed in pancreatic cancer: implications for cell proliferation and therapy

The results of a study, by Devenney et al

However, a more recent study observed that physiological levels of oncogene (KRAS G12D and MYC) expression could trigger a NRF2-dependent antioxidant response to downregulate ROS levels in cells [8]

, A recent 5-year follow-up of patients undergoing cataract surgery in the UK in 20002001 revealed lower mortality than in the general population