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ACSL4 is highly expressed in OA synovial tissue, while the key antioxidant enzyme GPX4 expression is significantly reduced

These pathways include mitochondrial autophagy, iron homeostasis regulation, and lipid peroxidation induction and ROS production

PMID 21523732

They found that palm oil tocotrienols at the dose of 100 mg/kg body weight significantly reduced the level of thiobarbituric acidreactive substance in the femur while significantly increasing glutathione peroxidase activity compared to the control group

Enhanced Gut Health Athletes often experience gastrointestinal issues due to stress and rigorous diets

To accomplish this, glucose transport to the brain is increased [62] while increased cerebral reliance on KB metabolism reduces the need for glucose consumption